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Fungal Therapy

Radioimmunotherapy kills pathogens via promotion of fungal cell apoptosis-like death

Published in TB and Outbreaks Week, July 4th, 2006

Radioimmunotherapy kills pathogens through the promotion of fungal cell apoptosis-like death.

According to a study from the United States, "The usefulness of radioimmunotherapy (RIT) for infectious diseases was recently demonstrated for several fungal and bacterial infections, but the mechanisms by which RIT is effective against microbes are uncertain.

"We investigated the interaction between polysaccharide capsule-binding 18B7 monoclonal antibodies (MAbs) labeled with alpha-emitter Bi-213 and Cryptococcus neoformans cells as well as between Bi-213-18B7 and components of immune system, both in vitro and in vivo."

"For...

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