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HIV/AIDS Pathogenesis

HIV-1 subtype C Envs elicit potent yet restricted neutralizing antibody response in early infection

Published in TB and Outbreaks Week, July 18th, 2006

HIV-1 subtype C Envs elicit potent yet restricted neutralizing antibody response in early infection.

According to a study from the United States, "Information about neutralizing antibody responses in subtype C-infected individuals is limited, even though this viral subtype causes the majority of AIDS cases worldwide.

"Here we compared the course and magnitude of the autologous neutralizing antibody (NAb) response against viral envelope (Env) glycoproteins present during acute and early infection with subtypes B and C human immunodeficiency virus type 1 (HIV-1)."

"NAb responses were evaluated in 6 subtype B-infected and 11 subtype...

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