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Prions

Studies from the United States, United Kingdom and Germany add new findings to prions body of knowledge

Published in TB and Outbreaks Week, August 15th, 2006

New findings from the United States, United Kingdom and Germany describe advances in prions.

Study 1: Ingested prion protein crosses the intestinal barrier and passes rapidly into lymph.

"The central nervous system is the ultimate target of prions, the agents responsible for fatal neurodegenerative diseases known as transmissible spongiform encephalopathies (TSEs). The neuroinvasive phase and its related clinical signs take place after a long incubation period.

"During this asymptomatic phase, however, active transport and replication of the infectious agent take place in peripheral sites," wrote investigators in the United...

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