Fungal Infection Prognostics
Antifungal susceptibility test results do not predict early clinical outcome in cryptococcosis
Published in TB and Outbreaks Week, August 29th, 2006
"The in vitro susceptibilities of Cryptococcus neoformans isolates from consecutive human immunodeficiency virus-positive and -negative patients to the antifungal agents fluconazole, amphotericin B, and flucytosine were determined by different techniques, including the CLSI method, Etest, and broth microdilution in yeast nitrogen base (YNB) medium, during a multicenter prospective study in France.
"The relationship between the in vitro data and the clinical outcome 2 weeks after the initiation of antifungal therapy was assessed. In...
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