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TB & Outbreaks Week

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Mycobacterium Tuberculosis Diagnostics



Combined molecular techniques types Mycobacterium tuberculosis strains



September 19th, 2006

A combination of molecular techniques may be used to type Mycobacterium tuberculosis strains.

According to a study from England, "While high-copy-number IS6110-based restriction fragment length polymorphism (HCN-RFLP) is the gold standard for typing most Mycobacterium tuberculosis strains, the time taken for culturing and low throughput make it impractical for large-scale prospective typing of large numbers of isolates.

"The development of a new method, mycobacterial interspersed repetitive units (MIRU), a variation of the original variable-number tandem repeat (VNTR) technique, may provide a viable alternative."

...


Source: TB & Outbreaks Week (2006-09-19)

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