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Mycobacterium Tuberculosis Diagnostics
Genotyping rapidly detects multidrug-resistant Mycobacterium tuberculosis strain mutations
September 19th, 2006
A PCR-based reverse hybridization genotype assay rapidly detects multidrug-resistant Mycobacterium tuberculosis strain mutations. "A novel PCR-based reverse hybridization method Genotype MTBDR assay (Hain Lifescience GmbH, Nehren, Germany) was evaluated for rapid detection of rifampin (RIF) and isoniazid (INH) resistance in Turkish Mycobacterium tuberculosis isolates. "The Genotype MTBDR assay is designed to detect mutations within the 81-bp hotspot region of rpoB and mutations at katG codon 315," wrote investigators in Turkey. According to C. Cavusoglu and colleagues at Ege University Medical Faculty in Izmir, "A...
Source: TB & Outbreaks Week (2006-09-19)
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