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TB & Outbreaks Week

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Skeletal Tuberculosis Diagnostics



Skeletal tuberculosis rapidly diagnosed by real-time PCR



September 19th, 2006

Skeletal tuberculosis can be rapidly diagnosed by real-time PCR.

"We identified Mycobacterium tuberculosis DNA using real-time polymerase chain reaction on a specimen from an osteolytic lesion of a femoral condyle, in which the frozen section demonstrated granulomas. The process was much more rapid than is possible with culture," investigators in the United States report.

According to the authors, "The rapid detection of M. tuberculosis and the concomitant exclusion of granulomatous disease caused by nontuberculous mycobacteria or systemic fungi are necessary to appropriately treat skeletal tuberculosis. The detection and identification...


Source: TB & Outbreaks Week (2006-09-19)

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