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TB & Outbreaks Week

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Tuberculosis Diagnostics



Interferon-gamma assays superior to tuberculin skin tests



September 19th, 2006

Interferon-gamma assays are superior to tuberculin skin tests for the diagnosis of Mycobacterium tuberculosis infection.

"The clinical usefulness of ex vivo interferon-gamma assays may largely depend on the assay format and epidemiological status of tuberculosis (TB) in the region studied. From July 2004 to June 2005 a prospective comparison study was undertaken at a tertiary referral hospital in South Korea.

"The results of tuberculin skin tests (TST) and the commercially available QuantiFERON-TB Gold (QFT-G) and T SPOT-TB (SPOT) assays were compared in an intermediate TB-burden country," wrote investigators in South Korea.

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Source: TB & Outbreaks Week (2006-09-19)

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