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Tuberculosis Pathophysiology
Active tuberculosis patients have increased anti-CCP and IgM rheumatoid factor titers
September 19th, 2006
Many active tuberculosis patients have increased titers of anticyclic citrullinated proteins and immunoglobulin M rheumatoid factor titers. In a recently published report, investigators in Israel conducted a study to "determine the prevalence of anti-cyclic citrullinated proteins (anti-CCP) and IgM rheumatoid factor (RF) in sera of patients with TB compared with healthy controls." "Forty-seven consecutive patients with recently diagnosed active pulmonary TB and 39 healthy controls were studied. Data were collected by questionnaire on clinical features of the disease, duration of symptoms, fever, cough, arthralgia, myalgia, sicca symptoms. ...
Source: TB & Outbreaks Week (2006-09-19)
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