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TB & Outbreaks Week

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Yersinia Pathogenesis



H-NS represses Y. enterocolitica inv transcription via competition with RovA



September 19th, 2006

H-NS represses Yersinia enterocolitica inv transcription via competition with RovA and interaction with YmoA.

According to recent research from the United States, "Yersinia enterocolitica is able to efficiently invade Peyer's patches with the aid of invasin, an outer member protein involved in the attachment and invasion of M cells.

"Invasin is encoded by inv, which is positively regulated by RovA in both Y. enterocolitica and Yersinia pseudotuberculosis while negatively regulated by YmoA in Y. enterocolitica and H-NS in Y. pseudotuberculosis."

"In this study," said the authors, "we...


Source: TB & Outbreaks Week (2006-09-19)

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