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Genetics & Genomics

 Trypanosoma rangeli histone gene sequence serves as a differential marker

Published in TB and Outbreaks Week, September 26th, 2006

According to a study from Columbia, Trypanosoma rangeli histone H2A gene sequence serves as a differential marker for KP1 strains.

"T. rangeli has recently been divided in two primary lineages denoted as KP1+ and KP1- strains because of epidemiological and evolutionary interest in the molecular differentiation of these two groups," wrote C. Cuervo and colleagues, University of Javeriana.

"We report the molecular characterization of the genes encoding histone H2A protein from a T rangeli KP1+ strain (H14), its comparison to T rangeli KPI- strain (C23) histone H2A coding genes [Puerta, C., Cuervo, P., Thomas, M.C., Lopez, M.C., 2000,...

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