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Tuberculosis Prognostics

Serum interleukin-2 and neopterin levels assess active pulmonary tuberculosis treatment

Published in TB and Outbreaks Week, October 3rd, 2006

Serum interleukin-2 and neopterin levels are useful markers for assessing active pulmonary tuberculosis treatment.

According to a study from Turkey, "Macrophages and T cells are responsible for the main immune response to tuberculosis by secreting many cytokines and other substances.

"The aim of this study was to determine the effects of multidrug treatment on serum levels of interleukin-2 (IL-2), secreted by activated T cells, and of neopterin, secreted by macrophages and monocytes, in patients with pulmonary tuberculosis."

"The study included 30 patients with active pulmonary tuberculosis, confirmed by the detection of acid-fast...

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