Mycobacteria
New data from the United States, United Kingdom and Germany lluminates research in mycobacteria
Published in TB and Outbreaks Week, October 3rd, 2006
Study 1: Mycobacterium tuberculosis LprA is a lipoprotein agonist of TLR2 that regulates innate immunity and APC function.
According to a study from the United States, "TLR2 recognizes components of Mycobacterium tuberculosis (Mtb) and initiates responses by APCs that influence both innate and adaptive immunity. Mtb lipoproteins are an important class of TLR2 ligand, but only two, LpqH and LprG, have been characterized to date."
"In this study, we characterize a third Mtb lipoprotein, LprA, and determine its effects on...
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