Cancer Marker
p16INK4 overexpression is a reliable marker of HPV-induced oral high-grade squamous dysplasia
Published in TB and Outbreaks Week, October 3rd, 2006
According to a recently published report from the United States, "Human papillomavirus (HPV) infection has been implicated in the development of high-grade squamous dysplasia and carcinoma of the oral cavity in the absence of other known risk factors such as smoking.
"HPV-induced oral dysplasia or carcinoma may be a unique tumor entity in terms of biologic behavior and treatment decisions. In detecting such cases, most reported studies have used techniques that are less sensitive than DNA amplification."
"Recent reports...
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