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West Nile Virus Therapy

Studies from Yale University describe new findings in west nile virus therapy

Published in TB and Outbreaks Week, November 28th, 2006

Current study results from the report, "Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes," have been published. "West Nile virus, a member of the Flavivirus genus, causes fever that can progress to life-threatening encephalitis. The major envelope glycoprotein, E, of these viruses mediates viral attachment and entry by membrane fusion," researchers in the United States report.

"We have determined the crystal structure of a soluble fragment of West Nile virus E. The structure adopts the same overall fold as that of the E proteins from dengue and tick-borne encephalitis viruses. The conformation of domain II is different from that...

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