New plague therapy study findings have been reported by scientists at Institute of Microbiology and Epidemiology

Researchers detail in "Genome-wide transcriptional response of Yersinia pestis to stressful conditions simulating phagolysosomal environments," new data in plague. According to recent research published in the journal Microbes and Infection, "Yersinia pestis is a Gram-negative coccobacillus causing the dangerous disease, plague. Survival of Y. pestis within host macrophages is important in the initial stages of infection. In our present work, DNA microarray was used to determine the expression profiles of Y. pestis strain 201 in response to in vitro simulating conditions of Mg(2+) limitation, polymyxin treatment and oxidative stress that could be found in phagolysosomal...

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