Tuberculosis Genetics
Studies conducted at University of Johannesburg, Department of Biochemistry on tuberculosis genetics recently published
Published in TB and Outbreaks Week, January 9th, 2007
Fresh data on tuberculosis are presented in the report "Association of HLA-DR, -DQ, and vitamin D receptor alleles and haplotypes with tuberculosis in the Venda of South Africa. The vitamin D receptor (VDR) and the human leukocyte antigen (HLA) class II complex affect innate and/or adaptive immunity against Mycobacterium tuberculosis. HLA-DRB1, HLA-DQB1, and VDR gene (VDR) polymorphisms were previously associated with tuberculosis (TB) and are here investigated as candidates for TB susceptibility in the Venda population of South Africa," researchers in South Africa report.
"Genomic DNA from 95 patients with pulmonary tuberculosis (PTB) and 117 ethnically matched,...
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