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Plague

The virulence of the plague bacillus: a "virus" involved...

Published in TB and Outbreaks Week, March 6th, 2007

During Middle Age, the plague decimated almost one third of the European population in less than 3 years. Why is the plague bacillus so pathogenic' Researchers from the Institut Pasteur have discovered that the infection of the ancestral form of the bacillus by a bacterial virus (phage) has been one of the steps that have led to the emergence of such a dreadful organism. For plague specialists, this discovery is a key step towards understanding the pathogenic mechanisms specific to the plague bacillus, and, eventually, towards the development of effective methods for combating the disease.

The plague is far from being eradicated. It continues to rage in various...

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