Current study results from the report, "Contributions of the lymphocytic choriomeningitis virusglycoprotein and polymerase to strain-specific differences in murineliverpathogenicity," have been published. According to a study from Zurich, Switzerland, "Hepatic involvement is commonly observed in arenavirus infections, but the viral determinants of liver disease are only partially understood. Here we exploited newly developed reverse-genetic techniques with Lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, to address specifically the contribution of the viral glycoprotein (GP) to liver pathogenicity."
"It is well established that strain WE, but not...
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