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Tuberculosis Vaccines

Findings from University of Rome, Department of Neuroscience provide new insights into tuberculosis vaccines

Published in TB and Outbreaks Week, March 27th, 2007

Investigators publish new data in the report "BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression." According to recent research from Rome, Italy, "Increasing evidence is now available showing that CD1-restricted T cell responses against non-peptide mycobacterial antigens could play a role in the immune resistance against tuberculosis. BCG, widely used in anti-tubercular vaccination, shares various constituents with Mycobacterium tuberculosis, but does not provide full protection."

"In the present study we have investigated the pattern of group 1 CD1 molecule expression in adherent mononuclear cells (AMNC) of...

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