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Escherichia Coli

Study results from Royal Free and University College update understanding of Escherichia coli

Published in TB and Outbreaks Week, May 22nd, 2007

Data detailed in "Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models" have been presented. According to recent research published in the journal Cellular Microbiology, "Tir, the translocated intimin receptor of enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC) and Citrobacter rodentium, is translocated into the host cell by a filamentous type III secretion system. Epithelial cell culture has demonstrated that Tir tyrosine phosphorylation is necessary for attaching effacing (A/E) lesion formation by EPEC and...

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