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West Nile Virus

Researchers from National Institutes of Health discuss findings in West Nile Virus

Published in TB and Outbreaks Week, September 18th, 2007

"West Nile virus ( WNV) is endemic in the United States. It is transmissible by blood transfusion, and the nation's blood supply is currently screened for WNV," scientists in the United States report.

"Documented transmission of WNV infection through red blood cell ( RBC) units in which the plasma co-component had a low viral load could be explained, in at least 1 instance, by cell-association of WNV; in this case, the RBC unit was released as negative by minipool nucleic acid testing ( NAT) performed on plasma but was intermittently NAT-positive when subsequently tested as an individual sample. We hypothesized that a proportion of WNV bound to blood cells and was not...

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