Tuberculosis

Reports from Imperial College London highlight recent research in tuberculosis

Published in TB and Outbreaks Week, October 2nd, 2007

Scientists discuss in "Astrocyte-leucocyte interactions and the mechanisms regulating matrix degradation in CNS tuberculosis" new findings in tuberculosis. According to recent research from London, the United Kingdom, "The CNS (central nervous system) has a unique pattern of immune response to infection. TB (tuberculosis) of the CNS is devastating with widespread tissue destruction."

"In TB, astrocyte-leucocyte interactions are key in regulating MMP (matrix metalloproteinase) activity and are regulated by complex signalling pathways. A synergistic interaction between interferon gamma and monocyte-derived mediators drives high-level astrocyte MMP-9 secretion; this and...

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Source: TB and Outbreaks Week (2007-10-02)

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