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HIV/AIDS Co-Infection

Report summarizes HIV/AIDS co-infection study findings from S. Danaviah and co-researchers

Published in TB and Outbreaks Week, October 16th, 2007

"Approximately 2 million South Africans are HIV/TB coinfected, and many develop skeletal disease. The resurgence of spinal tuberculosis, including atypical forms, is due largely to HIV-associated immune suppression," scientists writing in the journal Clinical Orthopaedics and Related Research report.

"We investigated the impact of HIV coinfection on the histological features of the disease and the occurrence of atypical opportunistic organisms in infectious spondylitis in an HIV/TB endemic region. We analyzed blood and tissue biopsies from 60 patients with tuberculous spondylitis. Investigations included full blood counts, CD4/CD8 counts, HIV-1 serology and RNA...

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