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West Nile Virus

New west nile virus research from Georgia State University, Department of Biology described

Published in TB and Outbreaks Week, November 6th, 2007

New research, 'Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts,' is the subject of a report. According to recent research published in the Journal of Virology, "Although lineage I West Nile virus (WNV) strain Eg101 induced beta interferon (IFN-beta) production as early as 12 h after infection in primary mouse embryo fibroblasts and did not inhibit the JAK-STAT signaling pathway, it was still able to replicate efficiently. To gain insights about possible viral countermeasures used by this virus to suppress the host response, the cell transcriptional profile and the...

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