Infectious Mononucleosis
Researchers from Tufts University, Medical Department report on findings in infectious mononucleosis
Published in TB and Outbreaks Week, November 20th, 2007
According to recent research from the United States, "Peripheral blood memory B cells latently infected with EBV bear somatic mutations and are typically isotype switched consistent with being classical Ag-selected memory B cells. In this work, we performed a comparative analysis of the expressed Ig genes between large sets of EBV-infected and uninfected peripheral blood B cells, isolated from the same infectious mononucleosis patients, to determine whether differences exist that could reveal the influence of EBV on the production and maintenance of these cells."
"We observed that EBV+ cells on average accumulated more somatic hypermutations than EBV- cells. In...
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