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Leishmaniasis

New leishmaniasis findings from Iran University, Medical Department described

Published in TB and Outbreaks Week, December 4th, 2007

"Cutaneous leishmaniasis (CL) is a major health problem in endemic areas of Iran," scientists in Iran report.

"The pentavalent antimony (SbV) based drug Glucantime is the first line of treatment for CL in Iran, but recently SbV-resistant Leishmania tropica isolates derived from unresponsive patients were reported. We show in this study that these resistant parasites are cross-resistant to the other SbV-containing drug Pentostam and at least for one isolate also to amphotericin B. However, these resistant isolates were shown to be sensitive to miltefosine and paromomycin," wrote R. Hadighi and colleagues, Iran University, Medical Department.

The...

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