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Dengue Fever Immunology

Data from National Institute of Infectious Disease, Infectious Diseases Department provide new insights into dengue fever immunology

Published in TB and Outbreaks Week, December 4th, 2007

Research findings, 'Dengue hemorrhagic fever with special emphasis on immunopathogenesis,' are discussed in a new report. "Dengue virus infections are a serious cause of morbidity and mortality in most tropical and subtropical areas of the world; Southeast and South Asia, Central and South America, and the Caribbean. Dengue virus infection can be asymptomatic or causes two forms of illness, dengue fever (DF) and dengue hemorrhagic fever (DHF), which is the severe form of dengue illness and often fatal," scientists in Tokyo, Japan report.

"Pathogenesis of DHF has been analyzed, and two mechanisms are considered to be responsible. These include dengue serotype...

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