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Findings in life sciences reported from Raul Carrea Institute for Neurological Research, Department of Neurology

Published in TB and Outbreaks Week, December 11th, 2007

A report, 'Monocyte-derived dendritic cells in multiple sclerosis: the effect of bacterial infection,' is newly published data in Journal of Neuroimmunology. According to recent research published in the Journal of Neuroimmunology, "We investigated whether monocyte-derived dendritic cells (MDDCs) generated in vitro from bacteria-infected MS patients modified autoreactive T cells activation patterns. T cell clones (TCCs) stimulated with MDDCs from infected MS patients responded with maximal proliferation, inducing IL-12, IL-17 and IFN-gamma secretion, at concentrations significantly lower than after incubation with MDDCs isolated from uninfected individuals and bacterial...

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