Antifungals
New data from University of Trieste, Department of Pharmaceutical Sciences illuminate research in antifungals
Published in TB and Outbreaks Week, January 1st, 2008
Current study results from the report, 'Synthesis, antifungal and antimycobacterial activities of new bis-imidazole derivatives, and prediction of their binding to P450(14DM) by molecular docking and MM/PBSA method,' have been published. "New bis-imidazole derivatives have been synthesized and their antifungal and antimycobacterial activity was determined. Almost all compounds exhibited a moderate to good activity against two clinical isolates of Candida albicans 3038 and Candida glabrata 123," scientists in Trieste, Italy report.
"The same compounds showed an interesting killing activity against Mycobacterium tuberculosis H(37)Rv reference strain. Docking...
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