Tuberculosis

Research on tuberculosis described by scientists at University of Paris

Published in TB and Outbreaks Week, January 22nd, 2008

According to recent research from Le Kremlin-Bicetre, France, "Latent tuberculosis infection ( LTBI) is detected with the tuberculin skin test ( TST) before anti-TNF therapy. We aimed to investigate in vitro blood assays with TB-specific antigens ( CFP-10, ESAT-6), in immune-mediated inflammatory diseases ( IMID) for LTBI screening."

"Sixty-eight IMID patients with ( n = 35) or without ( n = 33) LTBI according to clinicoradiographic findings or TST results ( 10 mm cutoff value) underwent cell proliferation assessed by thymidine incorporation and PKH-26 dilution assays, and IFN gamma-release enzyme-linked immunosorbent spot ( ELISPOT) assays with TB-specific antigens. In...

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Source: TB and Outbreaks Week (2008-01-22)

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