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Tuberculosis

Scientists at Complutense University detail research in tuberculosis

Published in TB and Outbreaks Week, January 22nd, 2008

"Mycobacterium bovis and Mycobacterium caprae are zoonotic bacteria that cause tuberculosis with several clinical manifestations. We have evaluated the susceptibility to anti - tuberculosis drugs of a panel of Spanish isolates of animal origin," scientists writing in the journal Tuberculosis report.

"The analysis of the sequence of the main genes involved in resistance was performed in 41 M. bovis and five M. caprae. The katG, inhA, rpsL, embB and gyrA genes had single nucleotide polymorphisms, not previously described in other organisms of the complex. Thirty-two M. bovis and three M. caproe isolates were tested for susceptibility to isoniazid (INH), rifampin,...

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