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Influenza

Research in the area of influenza reported from M.A. Hoelscher and colleagues

Published in TB and Outbreaks Week, January 29th, 2008

"Highly pathogenic avian H5N1 influenza viruses that are currently circulating in southeast Asia may acquire the potential to cause the next influenza pandemic. A number of alternate approaches are being pursued to generate cross-protective, dose-sparing, safe, and effective vaccines, as traditional vaccine approaches, i.e., embryonated egg-grown, are not immunogenic," scientists writing in the journal Clinical Pharmacology & Therapeutics report.

"We developed a replication-incompetent adenoviral vector-based, adjuvant- and egg-independent pandemic influenza vaccine strategy as a potential alternative to conventional egg-derived vaccines. In this paper, we...

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