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Meningitis Animal Studies

Scientists at University of Copenhagen, National Center for Antimicrobials and Infection Control detail research in meningitis animal studies

Published in TB and Outbreaks Week, February 19th, 2008

A new study, 'Impact of bacteremia on the pathogenesis of experimental pneumococcal meningitis,' is now available. According to recent research from Copenhagen, Denmark, "Bacteremia plays a major role in the outcome of pneumococcal meningitis. This experimental study investigated how bacteremia influences the pathophysiologic profile of the brain."

"Rats with Streptococcus pneumoniae meningitis were randomized to 1 of 3 groups of infected study rats: (1) rats with attenuated bacteremia resulting from intravenous injection of serotype-specific pneumococcal antibody, (2) rats with early-onset bacteremia resulting from concomitant intravenous infection, or (3) a...

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