Published in TB and Outbreaks Week, February 26th, 2008
"Using Acanthamoeba castellanii as a host cell, we have previously identified IcsC (Legionella cytotoxic suppressor), a paralogue of the lipid A disaccharide synthase lpxB, as a cytotoxic factor of L. pneumophila. A bioinformatic analysis of the genome revealed that L. pneumophila is unique in harbouring two paralogues of lpxB...
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