Life Sciences
New findings reported from Arizona State University, Department of Bioengineering describe advances in life sciences
Published in TB and Outbreaks Week, March 4th, 2008
Research findings, 'Tentacle Probes: differentiation of difficult single-nucleotide polymorphisms and deletions by presence or absence of a signal in real-time PCR,' are discussed in a new report. "False-positive results are a common problem in real-time PCR identification of DNA sequences that differ from near neighbors by a single-nucleotide polymorphism (SNP) or deletion. Because of a lack of sufficient probe specificity, post-PCR analysis, such as a melting curve, is often required for mutation differentiation," scientists in the United States report.
"Tentacle Probes, cooperative reagents with both a capture and a detection probe based on specific cell-targeting...
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