Tuberculosis Vaccines
Research on tuberculosis vaccines discussed by L. Mederos and co-researchers
Published in TB and Outbreaks Week, March 4th, 2008
A new study, 'Analysis of the structure of mycolic acids of Mycobacterium simiae reveals a particular composition of alpha-mycolates in strain 'habana' TMC 5135, considered as immunogenic in tuberculosis and leprosy,' is now available. "Structural analysis of mycolic acids from Mycobacterium simiae (including some 'habana' strains) was carried out using (1)H-NMR and MS. Results indicated that this species presents a general pattern of alpha-, alpha'-and keto-mycolates. alpha-Mycolates were composed of a complex mixture of 82 to 89 carbon atoms (C82-C89), with the predominant molecular species containing two di-substituted cyclopropane rings," researchers in La Habana, Cuba report.
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