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Leishmaniasis
Research from Rajendra Memorial Research Institute of Medical Sciences, Division of Immunology provides new data on leishmaniasis
March 11th, 2008
Current study results from the report, 'Leishmania donovani: role of CD2 on CD4+ T-cell function in Visceral Leishmaniasis,' have been published. "In this study, we investigated whether alteration in the CD2 mediated coordination of an immune response was associated with down regulation of CD4 associated Th1 cell response during Visceral Leishmaniasis (VL). Leishmania donovani (Ld) infection in VL patients markedly reduced expression of CD2 cell surface antigen on CD4+ cells. T-cells of VL patients were mostly in G0/G1 stage of the cell cycle (98.20%) with little or no activity of protein kinase C-alpha (PKC-alpha) isoform," scientists writing in the journal Experimental...
Source: TB & Outbreaks Week (2008-03-11)
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