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TB & Outbreaks Week

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Leishmaniasis Genetics



Reports summarize leishmaniasis genetics study results from Safdarjung Hospital



March 11th, 2008

New investigation results, 'Genetic fingerprinting and identification of differentially expressed genes in isolates of Leishmania donovani from Indian patients of post-kala-azar dermal leishmaniasis,' are detailed in a study published in Parasitology. "Post-kala-azar dermal leishmaniasis (PKDL) is an unusual dermatosis that develops as a sequel in 5-15% of cured cases of kala-azar (KA) after months or years of treatment in India. Molecular differences are reported to exist between the KA and PKDL isolates which may underlie the diversity in clinical manifestations of the disease," researchers in India report.

"Here, arbitrary primed-PCR (AP-PCR) has been used for...


Source: TB & Outbreaks Week (2008-03-11)

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