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Life Sciences
Research results from T.J. Scriba and colleagues update understanding of life sciences
March 11th, 2008
A report, 'Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response,' is newly published data in The Journal of Immunology. According to a study from Observatory, South Africa, "We investigated whether the proinflammatory T cell cytokines IL-17 and IL-22 are induced by human mycobacterial infection. Remarkably, >20% of specific cytokine-producing CD4(+) T cells in peripheral blood of healthy, mycobacteria-exposed adults expressed IL-17 or IL-22." "Specific IL-17-and IL-22-producing CD4(+) T cells were distinct from each other and from Th1 cytokine-producing cells. These cells had phenotypic...
Source: TB & Outbreaks Week (2008-03-11)
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