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Tuberculosis
Data on tuberculosis described by researchers at University of Texas, Health Center
March 11th, 2008
Fresh data on tuberculosis are presented in the report 'NK cells lyse T regulatory cells that expand in response to an intracellular pathogen.' "We evaluated the capacity of NK cells to influence expansion of CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) in response to microbial Ags, using Mycobacterium tuberculosis as a model. We previously found that Tregs expand when CD4(+) cells and monocytes are exposed to M. tuberculosis," researchers in the United States report. "Addition of NK cells that were activated by monokines (IL-12, IL-15, and IL-18) or by exposure to M. tuberculosis-stimulated monocytes reduced Treg expansion in response to M....
Source: TB & Outbreaks Week (2008-03-11)
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