TB & Outbreaks Week
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Genetics & Genomics
Study data from V.M. Kovalenko et al provide new insights into genetics & genomics
March 11th, 2008
"Drug-induced liver injury, including drug-induced hepatotoxicity during the treatment of tuberculosis infection, is a major health problem with increasingly significant challenges to modem hepatology. Therefore, the assessment and monitoring of the hepatotoxicity of antituberculosis drugs for prevention of liver injury are great concerns during disease treatment," researchers in the United States report. "The recently emerged data showing the ability of toxicants, including pharmaceutical agents, to alter cellular epigenetic status, open a unique opportunity for early detection of drug hepatotoxicity. Here we report that treatment of male Wistar rats with...
Source: TB & Outbreaks Week (2008-03-11)
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