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TB & Outbreaks Week

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Hantavirus



Data on hantavirus reported by A. Markotic and co-researchers



March 11th, 2008

According to recent research from Zagreb, Croatia, "Hantaviruses cause two important human illnesses, hemorrhagic fever with renal syndrome (HERS) and hantavirus pulmonary syndrome (HPS). Both syndromes are believed to be immune-mediated diseases."

"Monocytes/macrophages are thought to be the main target cells for hantaviruses and important sources of and targets for cytokines/chemokines secretion. THP-1 cells have been used extensively as models for primary monocytes in biocompatibility research. The aim of our study was to determine if hantaviruses induce the same immunoreactions in THP-1 cells and primary monocytesl macrophages and might therefore be suitable for...


Source: TB & Outbreaks Week (2008-03-11)

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