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Escherichia Coli
New Escherichia coli study findings have been reported by scientists at Korea University
March 18th, 2008
"The role of periplasmic disulfide oxidoreductase DsbA in Shiga toxin-producing Escherichia coli O157:H7 (STEC) was investigated. Deletion of dsbA (Delta dsbA) significantly decreased cell motility and alkaline phosphatase activity in STEC," investigators in Seoul, South Korea report. "STEC Delta dsbA also showed greater sensitivity to menadione and under low pH conditions. Significant reductions in surface attachment to both biotic (HT-29 epithelial cells) and abiotic (polystyrene and polyvinyl chloride) surfaces were observed in STEC Delta dsbA. In addition, no biofilm formation was detected in STEC Delta dsbA compared to wild-type cells in glass capillary tubes under...
Source: TB & Outbreaks Week (2008-03-18)
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