TB & Outbreaks Week
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Hantavirus
Studies from L. Antoniukas and co-researchers in the area of hantavirus published
March 18th, 2008
"Recombinant strains of Saccharomyces cerevisiae, producing hantavirus Puumala nucleocapsid protein for diagnostics and as a candidate vaccine were analyzed for uptake and excretion of intermediary metabolites during process optimization studies of fed-batch bioreactor cultures. Concentrations of glucose, maltose, galactose, pyruvate, acetaldehyde, ethanol, acetate, succinate and formaldehyde (used as a selection agent) were measured in the culture medium in order to find a metabolite pattern, indicative for the physiological state of the producer culture," researchers in Vilnius, Lithuania report. "When the inducer galactose was employed as a growth substrate, the...
Source: TB & Outbreaks Week (2008-03-18)
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