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TB & Outbreaks Week

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Leishmaniasis



Researchers from University of Khartoum detail findings in leishmaniasis



March 18th, 2008

"Post-kala-azar dermal leishmaniasis (PKDL) is a recognized dermatosis that follows successful treatment of visceral leishmaniasis in the Sudan. This randomized and double-blind study aimed to assess safety, immunogenicity and curative potentials of a novel immunochemotherapy regimen in patients with persistent PKDL," scientists in Khartoum, Sudan report.

"Following informed consent, 30 patients were randomized to receive alum-precipitated autoclaved Leishmania major (Alum/ALM) vaccine + Bacille Calmette-Guerin (BCG) and sodium stibogluconate (SSG) or vaccine diluent and SSG. The SSG +Alum/ALM+BCG proved safe with minimal. local adverse events. In the SSG+vaccine group,...


Source: TB & Outbreaks Week (2008-03-18)

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