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Tuberculosis
Data on tuberculosis detailed by researchers at University of Stellenbosch
March 18th, 2008
According to recent research from South Africa, "Data concerning T helper cell phenotypes in response to Mycobacterium tuberculosis infection remain controversial. T lymphocyte intracellular interteukin-4 production in response to CD3 stimulation was determined by flow cytometry in 21 TB patients and 14 community controls." "In supplementary experiments the association of interleukin-4 expression with apoptosis was investigated. A low percentage of CD4 T cells in both patients and controls expressed high levels of interleukin-4 (IL-4(high)). A larger subset of both CD4 and CD8 Tcells of all subjects expressed low levels of intracellular IL-4 (IL-4(low)). Stimulated and...
Source: TB & Outbreaks Week (2008-03-18)
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