TB & Outbreaks Week
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Tuberculosis
Findings from New York University, Medical Department in tuberculosis reported
March 18th, 2008
"The host response to Mycobacterium tuberculosis includes macrophage activation, inflammation with increased immune effector cells, tissue necrosis, and cavity formation, and fibrosis, distortion, and bronchiectasis. To evaluate the molecular basis of the immune response in the lungs of patients with active pulmonary tuberculosis (TB), we used bronchoalveolar lavage to obtain cells at the site of infection," scientists writing in the journal Tuberculosis report. "Affymetrix GeneChip microarrays and cDNA nylon fitter microarrays interrogated gene expression in bronchoalveolar Lavage (BAL) cells from 11 healthy controls and 17 patients with active pulmonary TB. We...
Source: TB & Outbreaks Week (2008-03-18)
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