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TB & Outbreaks Week

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Tuberculosis



New tuberculosis study findings recently were reported by researchers at Aga Khan University



March 18th, 2008

"Household contacts (HCs) of patients with tuberculosis (TB) are at higher risk of infection as well as the development of active disease. Longitudinal tracking of antigen-specific cytokines after acute exposure may significantly advance our understanding of the dynamic changes in cytokine patterns associated with disease establishment," investigators in Karachi, Pakistan report.

"To achieve this objective, we carried out a prospective cohort study with healthy HCs after exposure to TB. The patterns of cytokines (gamma interferon [IFN-gamma] and interleukin 10 [IL-10]) in response to mycobacterial antigens (culture filtrate [CF] proteins) and nonspecific mitogens...


Source: TB & Outbreaks Week (2008-03-18)

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