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Leishmaniasis
New findings from University of Sao Paulo in the area of leishmaniasis published
March 25th, 2008
According to a study from Sao Paulo, Brazil, "The gene Ldccys1 enconding a cysteine proteinase of 30kDa from Leishmania (Leishmania) chagasi, as welt as the recombinant cysteine proteinase rLdccys1, obtained by cloning and expression of the Ldccys1 gene in the pHIS vector, were used to evaluate their ability to induce immune protective responses in BALB/c mice against L. (L.) chagasi infection. Mice were immunized subcutaneously with rLdccys1 plus Bacille Calmette Guerin (BCG) or Propionibacterium acnes as adjuvants or intramuscularly with a plasmid carrying the Ldccys1 gene (Ldccys1/pcDNA3) and CpG ODN as the adjuvant, followed by a booster with rLdccys1 plus CpG ODN." ...
Source: TB & Outbreaks Week (2008-03-25)
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